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. 2019 Oct 22;10:2499. doi: 10.3389/fimmu.2019.02499

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Copyright © 2019 Ferrer, Thomas, López Ortiz, Errasti, Charo, Romanowski, Gorgojo, Rodriguez, Carrera Silva and Gómez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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JUNV P enhances transcription levels of IRF-1, IFN-β, SOCS1, and SOCS3. HMDM cells were infected with C#1 or P strains of JUNV (MOI = 1) and after 1 dpi the transcription levels of (A) IRF-1, (B) SOCS1, (C) SOCS3, and (D) IFN-β, were studied by RT-qPCR. The Comparative Ct method (2^−ΔCT) was used to analyze the expression level of the target genes. Non-parametric One-way ANOVA followed by Dunn's multiple comparison test was used to detect significant differences between groups; *P < 0.05. The results are graphed as the median (min-max, horizontal line indicates the median) of five independent donors.