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Minocycline did not improve the cognitive impairment induced by GCI in mice. Learning curve of MWM represented poor spatial learning and memory of GCI animals (A). Minocycline treatment did not decrease latency on POD10 (B) or increase swim speed (C), crossings (D), time spent (E), as well as distance travelled (F) in the target quadrant on POD11. (*p < 0.05, **p < 0.01, compared with GCI + NS, n = 10).
