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(a) Mean cell-free DNA concentration during various phlebotomy time points before, during, and after chemoradiation therapy. ** Significance in the change in cell-free DNA concentration from the baseline to the 6-week posttreatment follow-up samples. (b) Detected mutated genes are indicated in the frequency histogram; type of mutation is superimposed in color. (c) Qualitative plot of mutations in circulating tumor DNA. Each column represents a unique patient.
