FIG 3.

Analysis of miR-7 targets involved in Alzheimer’s disease and the SREBP1 pathway. (A) Bioinformatic analysis of prominent miR-7 target genes involved in Alzheimer’s disease using GeneMania. Blue lines indicate pathway correlation, green lines indicate genetic interaction, and purple lines indicate coexpression. (B) Predicted human target genes of miR-7 involved in Alzheimer’s disease, showing the number of putative binding sites and conservation in mouse. (C) Human target genes of miR-7 involved in the SREBP1 pathway, showing the number of predicted binding sites and conservation in mouse. Analyses in panels B and C were performed using TargetScan 6.2.