Table 1.
Effects of nocturnal train noise on sleep disturbance, hemodynamic parameters, laboratory parameters, catecholamines
| Control | Noise30 | Noise60 | p (ANOVA) | |
|---|---|---|---|---|
| Peak dB(A) | 64.63 ± 8.62 | 74.9 ± 3.56 | 74.49 ± 4.02 | < 0.001 |
| LAeq dB(A) | 33.32 ± 4.58 | 52 ± 2.69 | 54.45 ± 2.6 | < 0.001 |
| Sleep disturbance (VAS 0–10) | 3.6 ± 2.06 | 6.62 ± 1.8 | 7.19 ± 1.71 | < 0.001 |
| Hemodynamic parameter | ||||
| HR mean | 59.5 ± 8.1 | 58.7 ± 8.2 | 59.6 ± 8.4 | 0.377 |
| HR max | 104.6 ± 14.2 | 106.5 ± 16.8 | 107.3 ± 12.6 | 0.283 |
| HR accel index | 155.1 ± 144.2 | 177.8 ± 176.1 | 168.4 ± 146.5 | 0.843 |
| BPsyst mean | 115.3 ± 13.8 | 116.9 ± 13.5 | 114.1 ± 13.9 | 0.294 |
| BPdiast mean | 72.90 ± 11 | 74.10 ± 10.4 | 72.7 ± 10.1 | 0.475 |
| BP rise index | 31.1 ± 39.7 | 30.8 ± 31.3 | 38.8 ± 45.4 | 0.879 |
| PTTmean | 333.7 ± 19.2 | 332.5 ± 24.8 | 332.7 ± 19.8 | 0.377 |
| PTTmax | 373.2 ± 43.2 | 380 ± 19.2 | 375.3 ± 45.4 | 0.641 |
| PTTmin | 281.6 ± 26.2 | 274.1 ± 27.2 | 272.9 ± 26.5 | 0.088 |
| Laboratory parameters | ||||
| CRP (mg/l) | 2.00 ± 7.73 | 1.96 ± 7.91 | 1.13 ± 1.89 | 0.969 |
| Neutrophils (%) | 52 ± 8.7 | 52.5 ± 9.0 | 52.8 ± 8.4 | 0.626 |
| Cortisol (μg/l) | 15.46 ± 5.11 | 15.55 ± 5.4 | 15.15 ± 4.42 | 0.519 |
| Glucose (mg/dl) | 86.8 ± 6.2 | 86.5 ± 6.6 | 88 ± 6.4 | 0.058 |
| Adrenalin (pg/ml) | 25.6 ± 22.0 | 23.0 ± 18.18 | 25.9 ± 21.6 | 0.295 |
| Noradrenalin (pg/ml) | 144.4 ± 109.7 | 144.6 ± 123.3 | 157.6 ± 113.6 | 0.570 |
| Dopamine (pg/ml) | 10.07 ± 10.8 | 9.02 ± 8.8 | 10.68 ± 9.2 | 0.506 |
| 8-Isoprostan (pg/ml) | 39.1 ± 20 | 40.5 ± 22.3 | 40.1 ± 20.4 | 0.697 |
Data are presented as mean ± SD
LAeq, dB long-term equivalent continuous sound level, PTT pulse transit time, BP blood pressure, HR accel index heart rate acceleration index