Table 3.
Comparison of intravitreal cytokine and growth factor levels between eyes with and without severe proliferative vitreoretinopathy.
| Molecular factor, pg/ml | With severe PVR | Without severe PVR | p |
|---|---|---|---|
| IL-6 | 0.51 ± 0.17 | 0.39 ± 0.31 | 0.37 |
| IL-8 | 2.15 ± 1.92 | 2.45 ± 8.22 | 0.93 |
| IL-1β | 1.15 ± 1.51 | 0.42 ± 0.71 | 0.13 |
| TNF-β | 8.26 ± 10.49 | 4.13 ± 5.13 | 0.23 |
| GM-CSF | 0.32 ± 0.02 | 0.31 ± 0.12 | 0.19 |
| IFN-γ | 6.29 ± 0.79 | 5.15 ± 4.57 | 0.68 |
| CRP | 36.61 ± 7.70 | 21.17 ± 16.16 | 0.03 |
| PlGF | 45.34 ± 47.89 | 25.50 ± 77.34 | 0.55 |
| PDGF-BB | 51.63 ± 30.55 | 22.45 ± 24.01 | 0.01 |
| VEGF | 170462 ± 287247 | 14489 ± 53632 | 0.003 |
| Ang2 | 71064 ± 74155 | 32486 ± 57994 | 0.16 |
Abbreviations:
PVR, proliferative vitreoretinopathy; IL-6, interleukin 6; IL-8, interleukin 8; IL-1β, interleukin 1 beta; TNF-β, tumor necrosis factor beta; GM-CSF, granulocyte macrophage colony stimulating factor; IFN-γ, interferon gamma; CRP, C reactive protein; PlGF, placental growth factor; PDGF-BB, platelet derived growth factor BB; VEGF, vascular endothelial growth factor; Ang2, angiopoietin 2.
Severe PVR was defined as PVR grade 5 or worse.