Table 1.
Population characteristics.
| Parameter | Median (25th and 75th percentile) or % |
|---|---|
| Age (years) | 48 (37, 60) |
| Sex (% male) | 45 |
| Systolic blood pressure (mmHg) | 125 (113, 137) |
| BMI (kg/m2) | 26.7 (23.9, 30.1) |
| Height (cm) | 170 (163, 177) |
| Weight (kg) | 77.8 (67.4, 88.9) |
| Smoking (%) | |
| non-smoker | 38 |
| ex-smoker | 34 |
| smoker | 28 |
| Years of schooling (%) | |
| <10 years | 17 |
| 10 years | 55 |
| >10 years | 27 |
| Alcohol consumption (ml/day) | 3.6 (0.7, 10.8) |
| Diabetes mellitus type 2 (%) | 7 |
| Hypertension (%) | 40 |
| Metabolic Syndrome (%) | 23 |
| eGFR (mL/min/1.73 m2) | 99 (88, 109) |
| LV structural echocardiographic parameters | |
| LVM (g) | 171 (138, 210) |
| LVMI (g/m2) | 90 (77, 106) |
| LVD (cm) | 4.9 (4.5, 5.2) |
| LVS (cm) | 2.9 (2.6, 3.2) |
| PWD (cm) | 0.96 (0.82, 1.07) |
| RWT | 0.39 (0.35, 0.44) |
| left atrial diameter (cm) | 3.8 (3.5, 4.2) |
| Aorta (cm) | 2.7 (2.5, 3.1) |
| LV systolic functional echocardiographic parameters | |
| LVEF (%) | 72 (66, 78) |
| Fractional Shortening (%) | 41 (36, 46) |
| LV diastolic functional echocardiographic parameters | |
| MV E-wave (cm/s) | 0.7 (0.6, 0.8) |
| MV A-wave (cm/s) | 0.6 (0.5, 0.7) |
| E/A ratio | 1.14 (0.93, 1.43) |
| MV duration A-wave (ms) | 133 (121, 147) |
| MV dec. Time (ms) | 179 (157, 203) |
| E/e′ ratio | 5.8 (4.9, 7.1) |
| Biochemical analysis | |
| BDNF (pg/ml) | 21,676 (17,767, 25,676) |
BMI – body mass index, eGFR – estimated glomerular filtration rate, LV – left ventricle, LVM – left ventricular mass, LVMI – left ventricular mass index, LVD – left ventricular diastolic diameter, LVS – left ventricular systolic diameter, PWD – posterior wall diameter, PWT – posterior wall thickness, EF – ejection fraction, MV – mitral valve, BDNF – brain derived neurotrophic factor.