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. 2019 Oct 28;9:15400. doi: 10.1038/s41598-019-51066-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Schematic representation of the strategy used to identify genes coexpressed with TMPRSS4 in public databases. (B) Protein-protein network interactions analysis using STRING. Nine of the genes were significantly interconnected (FDR < 0.05). (C) Significant positive correlation between TMPRSS4 and DDR1 expression in LUAD and LUSC patient samples from Bild, Lee and TCGA databases, and in Cancer Cell Line Encyclopedia (CCLE) and CIMA cell lines.