Table 3.  . Multivariate analysis of genetic and clinical associations with ligation after indomethacin.

Characteristic	Odds ratio (95% CI)	p-value
Gestational age (each additional week)	0.76 (0.60–0.96)	0.02*
Postnatal age at treatment (days, median, IQR)	1.0 (0.96–1.04)	0.91
Sex (males vs females)	0.50 (0.23–1.08)	0.08
Surfactant use (yes vs no)	9.77 (1.15–83.26)	0.04*
CYPC2C9*2 (rs1799853)	3.74 (1.34–10.44)	0.01*

*Statistical significance < 0.05.