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. Author manuscript; available in PMC: 2019 Oct 29.
Published in final edited form as: J Geriatr Psychiatry Neurol. 2018 Jul 10;31(4):203–210. doi: 10.1177/0891988718785774

Table 2.

Comparison of Top Canonical Pathways Between Groups After Adjusting for Systemic Inflammatory Response Syndrome.

Group Comparison Canonical Pathway P Value z
Scorea
D+ versus D− Complement system .007   2.0
D+ UTI+ versus None  n/a n/a
 D− UTI +
D+ UTI− versus elF4 and p70S6K .01 2
 D− UTI−
UTI+ versus UTI− Interferon   .002   2.5
Actin cytoskeleton    .00002 −3.3
Integrin   8.7 × I0−8 −2.9
Paxillin    .0003 −2.3
RhoA    .0004 −2.3
D+ UTI+ versus Interferon    .00004   2.5
 D+ UTI− Actin cytoskeleton    .004 −2.5
Integrin    .002 −2.5
Paxillin    .003 −2.5
Glioma invasiveness    .004 −2.2
D− UTI+ versus None n/a n/a
 D− UTI−

Abbreviations: D+, delirious; D−, not delirious; n/a, not applicable; UTI+, urinary tract infection present; UTI−, urinary tract infection absent.

a

z score: A positive z score indicates upregulation of the pathway. A negative z score indicates downregulation of the pathway.