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. Author manuscript; available in PMC: 2020 Sep 3.
Published in final edited form as: Anal Chem. 2019 Aug 15;91(17):11297–11305. doi: 10.1021/acs.analchem.9b02377

Figure 3.

Figure 3.

Comparison of predicted to actual activity (A), black bars denote the activity due to cryptotanshinone and gray bars represent the observed fraction activity at 10 μg mL−1. Cryptotanshinone’s MIC matches previous reports.46 Fractions SM-1, SM-3, and SM-5 were prioritized for synergy testing. SM-1 showed synergy with an ΣFIC of 0.38 (B) as did SM-3 with an ΣFIC of 0.19 (C). SM-5 is additive with an ΣFIC of 0.75 (D). Equation 2 was used to calculate ΣFICs.