Table 3.
Association of Black Race and Biomarkers With Incident Cardiovascular Disease
| Variable | Unadjusted HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|
| Women | ||
| Black race | 2.05 (1.32, 3.17) | 1.15 (0.69, 1.92) |
| Lp(a) | 1.23 (1.02, 1.47) | 1.15 (0.94, 1.41) |
| ANA | 1.35 (1.10, 1.65) | 1.25 (1.02, 1.55) |
| Osteoprotegerin | 1.51 (1.16, 1.98) | 1.48 (1.10, 1.99) |
| Urinary microalbumin | 1.73 (1.40, 2.15) | 1.67 (1.32, 2.12) |
| sRAGE | 0.38 (0.19, 0.73) | 0.43 (0.21, 0.87) |
| Men | ||
| Black race | 2.39 (1.64, 3.46) | 1.21 (0.76, 1.95) |
| Lp(a) | 1.33 (1.15, 1.56) | 1.15 (0.96, 1.38) |
| Leptin | 1.21 (1.00, 1.45) | 1.01 (0.84, 1.22) |
| hsCRP | 1.61 (1.34, 1.90) | 1.23 (1.00, 1.52) |
| d‐dimer | 2.13 (1.69, 2.68) | 1.54 (1.17, 2.01) |
| SDMA | 14.28 (3.20, 63.8) | 1.64 (0.32, 8.53) |
| sRAGE | 0.42 (0.23, 0.75) | 0.65 (0.36, 1.17) |
| hs‐cTnT | 1.92 (1.62, 2.26) | 1.53 (1.23, 1.91) |
All biomarkers were log transformed. ANA indicates antinuclear antibodies; HR, hazard ratio; hsCRP, high‐sensitivity C‐reactive protein; hs‐cTnT, high‐sensitivity cardiac troponin T; Lp(a), lipoprotein (a); SDMA, symmetric dimethyl arginine; sRAGE, soluble receptor for advanced glycation end products.