Table 1.
Baseline Characteristics in 5446 Patients 50 Years or Younger Who Underwent Primary Isolated CABG in Sweden Between 1995 and 2015 Before and After Inverse Probability of Treatment Weighting
| Unweighted | IPTW | |||||
|---|---|---|---|---|---|---|
| Men | Women | SMD | Mena | Womena | SMD | |
| Number of patients | 4514 (83) | 932 (17) | 5372.86 | 4562.74 | ||
| Age, y, mean (SD) | 46.8 (3.76) | 46.1 (4.35) | 0.152 | 46.7 (3.74) | 46.7 (3.70) | 0.006 |
| Non‐Nordic birth region | 695 (15.4) | 69 (7.4) | 0.254 | 768.9 (14.3) | 517.3 (11.3) | 0.089 |
| Education | 0.151 | 0.119 | ||||
| <10 years | 927 (30.7) | 186 (29.4) | 1100.0 (30.7) | 882.6 (29.7) | ||
| 10–12 years | 1463 (48.5) | 347 (54.9) | 1768.8 (49.3) | 1610.6 (54.3) | ||
| >12 years | 625 (20.7) | 99 (15.7) | 719.1 (20.0) | 474.4 (16.0) | ||
| Not married | 3011 (66.7) | 619 (66.4) | 0.006 | 3601.9 (67.0) | 3088.4 (67.7) | 0.014 |
| Disposable income | 0.058 | 0.093 | ||||
| Q1 (lowest) | 801 (26.4) | 159 (25.0) | 951.9 (26.3) | 738.8 (24.7) | ||
| Q2 | 739 (24.3) | 169 (26.5) | 887.3 (24.6) | 850.7 (28.4) | ||
| Q3 | 796 (26.2) | 159 (25.0) | 941.6 (26.1) | 778.6 (26.0) | ||
| Q4 (highest) | 700 (23.1) | 150 (23.5) | 832.2 (23.0) | 626.9 (20.9) | ||
| Body mass index, kg/m2, mean (SD) | 28.0 (4.25) | 27.4 (5.35) | 0.135 | 27.96 (4.40) | 28.13 (4.57) | 0.031 |
| Diabetes mellitus | 771 (17.1) | 312 (33.5) | 0.384 | 1033.9 (19.2) | 949.5 (20.8) | 0.039 |
| Hypertension (%) | 809 (17.9) | 214 (23.0) | 0.125 | 992.4 (18.5) | 889.6 (19.5) | 0.026 |
| Hyperlipidemia (%) | 1060 (23.5) | 180 (19.3) | 0.102 | 1237.0 (23.0) | 982.8 (21.5) | 0.036 |
| Peripheral vascular disease | 115 (2.5) | 51 (5.5) | 0.149 | 156.6 (2.9) | 159.8 (3.5) | 0.033 |
| eGFR, mL/min per 1.73 m2, mean (SD) | 89 (19) | 81 (27) | 0.360 | 87.83 (20.65) | 86.40 (21.25) | 0.070 |
| End‐stage renal disease | 81 (1.8) | 66 (7.1) | 0.259 | 136.1 (2.5) | 142.6 (3.1) | 0.036 |
| Chronic pulmonary disease | 81 (1.8) | 27 (2.9) | 0.073 | 104.4 (1.9) | 117.2 (2.6) | 0.042 |
| Prior myocardial infarction | 2193 (48.6) | 402 (43.1) | 0.110 | 2581.4 (48.0) | 2112.7 (46.3) | 0.035 |
| Prior PCI | 988 (21.9) | 216 (23.2) | 0.031 | 1185.3 (22.1) | 961.2 (21.1) | 0.024 |
| Heart failure | 281 (6.2) | 88 (9.4) | 0.120 | 347.2 (6.5) | 340.0 (7.5) | 0.039 |
| LV ejection fraction <50% | 0.121 | 0.060 | ||||
| >50% | 1265 (71.3) | 286 (76.1) | 1511.9 (71.8) | 1288.9 (73.9) | ||
| 30%–50% | 407 (22.9) | 68 (18.1) | 471.7 (22.4) | 348.2 (20.0) | ||
| <30% | 102 (5.7) | 22 (5.9) | 123.2 (5.8) | 107.4 (6.2) | ||
| Stroke | 129 (2.9) | 36 (3.9) | 0.056 | 162.0 (3.0) | 128.6 (2.8) | 0.012 |
| Atrial fibrillation | 81 (1.8) | 12 (1.3) | 0.041 | 96.2 (1.8) | 53.5 (1.2) | 0.051 |
| Cancer | 48 (1.1) | 26 (2.8) | 0.126 | 66.5 (1.2) | 70.1 (1.5) | 0.026 |
| Alcohol dependency | 117 (2.6) | 15 (1.6) | 0.069 | 135.8 (2.5) | 79.1 (1.7) | 0.055 |
| Off‐pump CABG | 557 (12.3) | 134 (14.4) | 0.060 | 684.3 (12.7) | 565.8 (12.4) | 0.010 |
| Number of grafts | 0.333 | 0.094 | ||||
| 1–2 | 957 (21.2) | 317 (34.0) | 1235.6 (23.0) | 1142.4 (25.0) | ||
| 3–4 | 2741 (60.7) | 482 (51.7) | 3187.5 (59.3) | 2724.4 (59.7) | ||
| >4 | 530 (11.7) | 60 (6.4) | 593.4 (11.0) | 385.0 (8.4) | ||
| Unknown | 286 (6.3) | 73 (7.8) | 356.3 (6.6) | 310.9 (6.8) | ||
| Type of graft | ||||||
| Internal mammary artery | 4225 (93.6) | 848 (91.0) | 0.098 | 5015.8 (93.4) | 4222.9 (92.6) | 0.031 |
| Bilateral mammary arteries | 104 (2.3) | 18 (1.9) | 0.026 | 120.8 (2.2) | 72.2 (1.6) | 0.049 |
| Radial artery graft | 128 (2.8) | 28 (3.0) | 0.010 | 149.6 (2.8) | 143.3 (3.1) | 0.021 |
| >1 arterial graft | 223 (4.9) | 44 (4.7) | 0.010 | 259.6 (4.8) | 210.5 (4.6) | 0.010 |
Numbers are n (%) unless otherwise noted. CABG indicates coronary artery bypass grafting; eGFR, estimated glomerular filtration rate; IPTW, inverse probability of treatment weighting; LV, left ventricular; PCI, percutaneous coronary intervention; SMD, standardized mean difference.
a
The overall numbers of patients in each group are not integers because of inverse probability of treatment weighting.