Table 4.

Regression analyses for association between the number of fractures and demographic and clinical variables with PROs^a (n = 935)^b.

	Coefficient (95% CI)
			OPAQ-SV
Variable	EQ-5D	EQ-VAS	Physical	Emotional	Symptom
Number of fractures	−0.0543	−4.682	−5.2196	−5.5403	−6.7456
	(−0.0722, −0.0363)	(−7.3076, −2.0573)	(−6.8898, −3.5493)	(−7.3200, −3.7607)	(−8.9615, −4.5298)
	p<.001	p=.001	p<.001	p<.001	p<.001
Age	−0.0046	−0.2843	−0.5164	−0.5217	−0.5137
	(−0.0058, −0.0034)	(−0.4175, −0.1512)	(−0.6680, −0.3647)	(−0.6627, −0.3807)	(−0.6807, −0.3466)
	p<.001	p<.001	p<.001	p<.001	p<.001
Male genderc	0.0045	2.6280	−0.1021	2.9503	−1.060
	(−0.0364, 0.0455)	(−0.8718, 6.1278)	(−3.7036, 3.4994)	(−0.5394, 6.4399)	(−5.6449, 3.5252)
	p=.827	p=.140	p=.955	p=.097	p=.649
BMI	−0.0036	−0.3243	−0.4211	−0.2736	−0.5592
	(−0.0063, −0.0009)	(−0.5697, −0.0789)	(−0.6587, −0.1836)	(−0.5031, −0.0441)	(−0.9131, −0.2054)
	p=.009	p=.010	p=.001	p=.020	p=.002
CCI	−0.0332	−3.4995	−2.703	−1.9865	−3.2203
	(−0.0430, −0.0235)	(−4.5141, −2.4849)	(−3.8029, −1.6035)	(−2.8830, −1.0899)	(−4.4874, −1.9532)
	p<.001	p<.001	p<.001	p<.001	p<.001

Abbreviations. BMI, body mass index; CCI, Charlson Comorbidity Index; CI, confidence interval; EQ-5D, European Quality of Life 5 Domains; EQ-VAS, European Quality of Life Visual Analog Scale; OPAQ-SV, Osteoporosis Assessment Questionnaire short-version.

^aModel included number of fractures, age, gender, BMI, and CCI only. p-values were adjusted to account for physician clustering.

^bIncludes participants who completed all PROs and had values for all variables used in the regression analysis.

^cReference was female gender.