Table 1.

Cell Migration Simulator Parameter Values

Symbol	Parameter	Value
Nm	number of motors	1000
Nc	number of clutches	850; 1000
Atot	total possible actin protrusion length	100 μm
Vp∗	maximal actin polymerization velocity	200 nm/s
kmod∗	maximal module birth rate	1 s−1
kcap	module capping rate	0.001 s−1
Iin	initial module length	5 μm
Imin	minimal module length	0.1 μm
kcell	cell spring constant	1000 pN/nm
nc,cell	number of cell body clutches	10
Fm	motor stall force	2 pN
Vm∗	unloaded motor velocity	120 nm/s
kon	clutch on-rate	1 s−1
koff∗	clutch unloaded off-rate	0.1 s−1
kin∗	maximal number of module motors	100
Vm∗	unloaded motor velocity	120 nm/s
nc∗	maximal number of module clutches	0.1xNc
kc	clutch spring constant	0.8 pN/nm
Fb	characteristic clutch rupture force	2 pN
ks	substrate spring constant	10 pN/nm