Gene expression profiling separates the progenitor cells from the differentiated cells
A. Schematic diagram of NSCs differentiating to GNP cells, glia, and neurons. The solid and dashed lines indicate distinct differentiation paths. B. Unsupervised hierarchical clustering of gene expression normalized by Z-score fails to identify the differentiation path of NSCs to GNP cells to glia. NSC, neural stem cell; Gcm, glial cell missing; GNP, Gcm-expressed neural progenitor.