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. 2019 Jun 11;17(3):297–304. doi: 10.1016/j.gpb.2018.12.009

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Nucleosome organization around TSSs fails to reveal the neural progenitor–progeny relationships

A. Normalized nucleosome occupancy pattern around TSSs. Genes are ascendingly ordered by nucleosome occupancy in NDRs (ranging from 150 bp upstream to 50 bp downstream of TSSs). The typical arrangement at −1, NDR, +1, +2, +3 nucleosomes, etc. is shown on the top. B. Clustering dendrogram of cell types based on normalized nucleosome occupancy in the NDRs fails to reveal the neural progenitor–progeny relationships. TSS, transcription start site; NDR, nucleosome-depleted region.