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H3K27me3 signal in the enhancers constructs the neural differentiation path
A. ROC curves of H3K9ac and H3K27me3 in the enhancers as predictors of gene activity using the top 1500 highly expressed genes as actual positives (top panels) and the bottom 1500 lowly expressed genes as actual positives (bottom panels). Unsupervised hierarchical clustering of normalized H3K9ac (B) and H3K27me3 (C) signal in the enhancers showing the differential grouping of lineage progenitors (NSC and GNP).
