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. 2019 Sep 20;16(11):1424–1429. doi: 10.7150/ijms.38080

Table 3.

Odds ratio (OR) and 95% confidence interval (CI) of clinical status and GAS5 rs145204276 genotypic frequencies in 579 patients with prostate cancer.

Variable Genotypic frequencies
rs145204276 ins/ins (N=263) ins/del + del/del (N=316) OR (95% CI) p value
PSA at diagnosis (ng/mL)
≤ 10 148 (56.3%) 161 (50.9%) 1.00 p=0.201
> 10 115 (43.7%) 155 (49.1%) 1.239 (0.892-1.721)
Pathologic Gleason grade group
1+2+3 216 (82.1%) 268 (84.8%) 1.00 p=0.386
4+5 47 (17.9%) 48 (15.2%) 0.823 (0.530-1.278)
Clinical T stage
1+2 223 (84.8%) 278 (88.0%) 1.00 p=0.264
3+4 40 (15.2%) 38 (12.0%) 0.762 (0.473-1.229)
Pathologic T stage
2 140 (53.2%) 166 (52.5%) 1.00 p=0.867
3+4 123 (46.8%) 150 (47.5%) 1.029 (0.741-1.427)
Pathologic N stage
N0 234 (89.0%) 296 (93.7%) 1.00 p=0.043*
N1 29 (11.0%) 20 (6.3%) 0.545 (0.301-0.988)
Seminal vesicle invasion
No 194 (73.8%) 258 (81.6%) 1.00 p=0.022*
Yes 69 (26.2%) 58 (18.4%) 0.632 (0.426-0.939)
Perineural invasion
No 63 (24.0%) 92 (29.1%) 1.00 p=0.163
Yes 200 (76.0%) 224 (70.9%) 0.767 (0.528-1.114)
Lymphovascular invasion
No 211 (80.2%) 271 (85.8%) 1.00 p=0.076
Yes 52 (19.8%) 45 (14.2%) 0.674 (0.435-1.044)
D'Amico classification
Low risk/
Intermediate risk
129 (49.0%) 151 (47.8%) 1.00 p=0.762
High risk 134 (51.0%) 165 (52.2%) 1.052 (0.758-1.459)

The ORs with analyzed by their 95% CIs were estimated by logistic regression models. * p value < 0.05 as statistically significant.