Table 3.
Variable | Genotypic frequencies | |||
---|---|---|---|---|
rs145204276 | ins/ins (N=263) | ins/del + del/del (N=316) | OR (95% CI) | p value |
PSA at diagnosis (ng/mL) | ||||
≤ 10 | 148 (56.3%) | 161 (50.9%) | 1.00 | p=0.201 |
> 10 | 115 (43.7%) | 155 (49.1%) | 1.239 (0.892-1.721) | |
Pathologic Gleason grade group | ||||
1+2+3 | 216 (82.1%) | 268 (84.8%) | 1.00 | p=0.386 |
4+5 | 47 (17.9%) | 48 (15.2%) | 0.823 (0.530-1.278) | |
Clinical T stage | ||||
1+2 | 223 (84.8%) | 278 (88.0%) | 1.00 | p=0.264 |
3+4 | 40 (15.2%) | 38 (12.0%) | 0.762 (0.473-1.229) | |
Pathologic T stage | ||||
2 | 140 (53.2%) | 166 (52.5%) | 1.00 | p=0.867 |
3+4 | 123 (46.8%) | 150 (47.5%) | 1.029 (0.741-1.427) | |
Pathologic N stage | ||||
N0 | 234 (89.0%) | 296 (93.7%) | 1.00 | p=0.043* |
N1 | 29 (11.0%) | 20 (6.3%) | 0.545 (0.301-0.988) | |
Seminal vesicle invasion | ||||
No | 194 (73.8%) | 258 (81.6%) | 1.00 | p=0.022* |
Yes | 69 (26.2%) | 58 (18.4%) | 0.632 (0.426-0.939) | |
Perineural invasion | ||||
No | 63 (24.0%) | 92 (29.1%) | 1.00 | p=0.163 |
Yes | 200 (76.0%) | 224 (70.9%) | 0.767 (0.528-1.114) | |
Lymphovascular invasion | ||||
No | 211 (80.2%) | 271 (85.8%) | 1.00 | p=0.076 |
Yes | 52 (19.8%) | 45 (14.2%) | 0.674 (0.435-1.044) | |
D'Amico classification | ||||
Low risk/ Intermediate risk |
129 (49.0%) | 151 (47.8%) | 1.00 | p=0.762 |
High risk | 134 (51.0%) | 165 (52.2%) | 1.052 (0.758-1.459) |
The ORs with analyzed by their 95% CIs were estimated by logistic regression models. * p value < 0.05 as statistically significant.