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. 2019 Aug 30;117(7):1364–1379. doi: 10.1016/j.bpj.2019.08.029

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© 2019 Biophysical Society.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Interaction of AE1 with cholesterol. (A) Snapshots from the atomistic simulations of each model in the rev-V conformation show the interactions of the mdAE1 dimer (orange and cyan ribbon) with cholesterol (yellow spheres). View is from the cytoplasmic side. The cdAE1 was omitted for clarity. Molecules of SM (blue spheres) and POPC (magenta spheres) are shown. (B) The volume in the mdAE1 dimer interface that is filled with lipids is shown in gray. See also Figs. S11 and S12. To see this figure in color, go online.