Table 2.

Sensitivity analysis for strength as a predictor of limited physical performance and for low ALM as a predictor of low strength across subgroups in the Canadian longitudinal study on aging cohort, 2011–2015

	N	Prevalence low HGS (%)	OR (95% CI) for impaired physical performance	P for interactiona		OR (95% CI) for low HGS
			Low HGS		Prevalence low ALM (%)	Low ALM	P for interactionb
Men
Overall	4725	21.5	4.51 (3.58, 5.68)		21.7	3.02 (2.59, 3.52)
Age
65–74	2878	14.8	4.50 (2.87, 7.04)	0.162	16.3	2.71 (2.14, 3.43)	0.777
≥75	1847	32.0	3.09 (2.34, 4.07)		30.0	2.59 (2.10, 3.19)
Nutritional risk (SCREEN II‐AB)
Yes	1332	24.2	3.09 (2.34, 4.07)	0.304	22.1	3.79 (2.87, 5.00)	0.058
No	3393	20.5	4.50 (2.89, 7.04)		21.5	2.74 (2.28, 3.30)
Heart disease
Yes	1029	25.4	4.79 (3.17, 7.24)	0.640	21.4	2.79 (2.04, 3.84)	0.558
No	3696	20.4	4.25 (3.21, 5.62)		21.8	3.11 (2.61, 3.71)
Kidney disease
Yes	173	28.9	2.74 (0.97, 7.76)	0.339	28.9	4.47 (2.19, 9.10)	0.264
No	4552	21.2	4.61 (3.64, 5.84)		21.4	2.95 (2.52, 3.45)
COPD
Yes	273	26.0	3.55 (1.54, 8.20)	0.565	30.4	3.39 (1.92, 5.99)	0.667
No	4452	21.2	4.58 (3.61, 5.82)		21.1	2.98 (2.54, 3.49)
Type 2 diabetes
Yes	630	27.6	4.21 (2.57, 6.90)	0.853	19.7	4.01 (2.66, 6.05)	0.163
No	4095	20.6	4.44 (3.41, 5.76)		22.0	2.93 (2.48, 3.45)
Women
Overall	4363	24.1	4.66 (3.67, 5.92)		13.7	2.46 (2.05, 2.95)
Age
65–74	2706	15.4	5.43 (3.39, 8.70)	0.013	11.5	2.44 (1.86, 3.21)	0.483
≥75	1657	38.2	2.69 (2.02, 3.58)		17.3	2.14 (1.65, 2.76)
Nutritional risk (SCREEN II‐AB)
Yes	1427	27.4	2.69 (2.02, 3.58)	0.867	14.0	2.07 (1.51, 2.81)	0.168
No	2936	22.4	5.43 (3.39, 8.70)		13.5	2.70 (2.16, 3.37)
Heart disease
Yes	519	28.7	3.01 (1.77, 5.11)	0.081	12.7	2.52 (1.49, 4.26)	0.947
No	3844	23.4	5.11 (3.90, 6.70)		13.8	2.47 (2.03, 2.99)
Kidney disease
Yes	142	31.0	3.30 (1.25, 8.67)	0.480	16.9	0.70 (0.26, 1.91)	0.012
No	4221	23.8	4.72 (3.69, 6.05)		13.6	2.58 (2.15, 3.10)
COPD
Yes	318	27.4	3.31 (1.64, 6.66)	0.314	15.7	2.22 (1.18, 4.15)	0.736
No	4045	23.8	4.85 (3.75, 6.26)		13.5	2.48 (2.05, 3.00)
Type 2 diabetes
Yes	376	27.4	4.48 (2.41, 8.34)	0.909	8.0	2.93 (1.38, 6.24)	0.663
No	3987	23.8	4.66 (3.59, 6.05)		14.2	2.47 (2.05, 2.98)

ALMI, appendicular lean mass index; COPD, chronic obstructive pulmonary diseases; HGS, handgrip strength; SCREEN II‐AB, abbreviated Seniors in the Community Risk Evaluation for Eating and Nutrition, version II, score < 38 was considered as at risk of poor nutritional state.

^aInteraction for absence/presence of low HGS and subgroup characteristics in the prediction of impaired physical performance.

^bInteraction for absence/presence of low ALM and subgroup characteristics in the prediction of low HGS.