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. 2019 Oct 23;36(22):3092–3102. doi: 10.1089/neu.2019.6415

FIG. 4.

FIG. 4.

CLP290-ehanced recovery of function with day 1 administration after traumatic brain injury (TBI). Animals were treated with CLP290 initiating 1 h (Tx0d), one day (Tx1d), two days (Tx2d) after injury or with vehicle alone. (A) w-ART performance was assessed four days after injury as measured by the latency to remove a sticker placed on the whiskers. Data reported as mean ± standard error of the mean (SEM), n = 7/group. Student t test: *p < 0.05 (CNT/Veh vs. TBI/Veh). #p < 0.017 (TBI/Veh vs. TBI/Tx1d), with Šidák multiple comparisons correction. (B) Rotarod performance was assessed four days after injury as measured by the latency to fall from the device. Data reported as mean ± SEM, n = 7/group. Student t test: *p < 0.05 (CNT/Veh vs. TBI/Veh). #p < 0.017 (TBI/Veh vs. TBI/Tx1d), with Šidák multiple comparisons correction.