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. 2019 Oct 22;6:229. doi: 10.3389/fmed.2019.00229

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Copyright © 2019 Williams, Baker, Guina, Hewitt, Lanning, Hill, May, Fogtman and Pittman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative plots of vital signs for subjects exposed to 25,000 cfu. (A–C) Representative temperature plots derived from body temperature (in °F) listings over the entire course of the study. The red vertical line represents the study day (@ 000 h) where antibiotic was administered. (D–F) Overlay plots for the same subjects in which body temperature changes (closed circles, in °F) are plotted with pulse rate (open circles) and respiration rate (X) over the first eight study days after exposure.