Table 4.
Percent of subjects showing re-appearance of more than 1 adverse event after termination of tetracycline treatment in operation whitecoat subjects exposed to aerosolized F. tularensis Schu S4.
| Duration of treatment | 1 g per day (0.25 g q.i.d) | 2 g per day (0.5 g q.i.d or 1 g b.i.d) | Totals |
|---|---|---|---|
| <14 days | NA | 6 of 11 subjects (54.5%) |
6 of 11 subjects (54.5%) |
| ≥14 days | 1 of 8 subjects (12.5%) |
8 of 44 subjects (18.2%)* |
9 of 52 subjects (17.3%)* |
| Totals | 1 of 8 subjects (12.5%) |
14 of 55 subjects (25.5%) |
15 of 63 subjects (23.8%) |
*
Significantly different from subjects treated <14 days (p < 0.05).