Table 2.
Characteristica | Case control status | All | |||||
---|---|---|---|---|---|---|---|
Non-case | Case | ||||||
N | % | N | % | N | % | p value | |
All | 36967 | 100 | 2719 | 100 | 39686 | 100 | |
Chronotype | 0.002 | ||||||
Definite morning type | 14220 | 38 | 955 | 35 | 15175 | 38 | |
More morning than evening type | 7678 | 21 | 563 | 21 | 8241 | 21 | |
Neither morning/evening type | 4923 | 13 | 385 | 14 | 5308 | 13 | |
More evening than morning type | 5511 | 15 | 424 | 16 | 5935 | 15 | |
Definite Evening type | 4635 | 13 | 392 | 14 | 5027 | 13 | |
Age | <0.001 | ||||||
40-49 years | 686 | 2 | 33 | 1 | 719 | 2 | |
50-59 years | 6423 | 17 | 283 | 10 | 6706 | 17 | |
60-69 years | 15562 | 42 | 969 | 36 | 16531 | 42 | |
70-79 years | 9605 | 26 | 963 | 35 | 10568 | 27 | |
80-89 years | 4691 | 13 | 471 | 17 | 5162 | 13 | |
Race/Ethnicityb | 0.049 | ||||||
White | 32316 | 87 | 2422 | 89 | 34738 | 88 | |
Black | 810 | 2 | 55 | 2 | 865 | 2 | |
Hispanic | 1525 | 4 | 82 | 3 | 1607 | 4 | |
Asian/Pacific Islander | 1486 | 4 | 105 | 4 | 1591 | 4 | |
Other | 830 | 2 | 55 | 2 | 885 | 2 | |
Smoking pack-yearsb | <0.001 | ||||||
Never smokers | 24731 | 67 | 1667 | 61 | 26398 | 67 | |
≤10 | 6517 | 18 | 500 | 18 | 7017 | 18 | |
11-20 | 2156 | 6 | 189 | 7 | 2345 | 6 | |
21-30 | 1172 | 3 | 103 | 4 | 1275 | 3 | |
≥31 | 1229 | 3 | 152 | 6 | 1381 | 3 | |
Unknown | 1162 | 3 | 108 | 4 | 1270 | 3 | |
BMI (kg/m2) | 0.011 | ||||||
15-24 | 17780 | 48 | 1236 | 45 | 19016 | 48 | |
25-29 | 10585 | 29 | 841 | 31 | 11426 | 29 | |
30-54.8 | 6826 | 18 | 492 | 18 | 7318 | 18 | |
Unknown | 1776 | 5 | 150 | 6 | 1926 | 5 | |
Alcohol consumption (g/day) b | <0.001 | ||||||
None | 10992 | 30 | 755 | 28 | 11747 | 30 | |
<20 | 21744 | 59 | 1580 | 58 | 23324 | 59 | |
≥20 | 2938 | 8 | 282 | 10 | 3220 | 8 | |
Unknown | 1293 | 3 | 102 | 4 | 1395 | 4 | |
Physical activity (hours per week) d | <0.001 | ||||||
0 to < 2.25 | 11226 | 30 | 951 | 35 | 12177 | 31 | |
2.25 to < 5.50 | 12430 | 34 | 915 | 34 | 13345 | 34 | |
5.50 to 24.00 | 13216 | 36 | 846 | 31 | 14062 | 35 | |
Unknown | 95 | 0 | 7 | 0 | 102 | 0 | |
Family history of breast cancerc | <0.001 | ||||||
No | 29867 | 81 | 2009 | 74 | 31876 | 80 | |
Yes | 6113 | 17 | 626 | 23 | 6739 | 17 | |
Unknown | 987 | 3 | 84 | 3 | 1071 | 3 | |
Age at menarche (years)b | 0.307 | ||||||
≤11 | 8546 | 23 | 669 | 25 | 9215 | 23 | |
12-13 | 20978 | 57 | 1499 | 55 | 22477 | 57 | |
≥14 | 7017 | 19 | 519 | 19 | 7536 | 19 | |
Unknown/Never | 426 | 1 | 32 | 1 | 458 | 1 | |
Age at 1st full-term pregnancy (years) b | 0.650 | ||||||
No full-term pregnancy | 8420 | 23 | 625 | 23 | 9045 | 23 | |
≤24 | 9967 | 27 | 710 | 26 | 10677 | 27 | |
25-29 | 11301 | 31 | 864 | 32 | 12165 | 31 | |
≥30 | 6758 | 18 | 485 | 18 | 7243 | 18 | |
Unknown | 521 | 1 | 35 | 1 | 556 | 1 | |
Breast feeding history (months) b | 0.031 | ||||||
Never pregnant | 6328 | 17 | 468 | 17 | 6796 | 17 | |
Pregnancy, but no live birth | 2055 | 6 | 155 | 6 | 2210 | 6 | |
0 | 5311 | 14 | 452 | 17 | 5763 | 15 | |
>0 and <6 | 6148 | 17 | 461 | 17 | 6609 | 17 | |
6-11 | 5445 | 15 | 373 | 14 | 5818 | 15 | |
≥12 | 11028 | 30 | 769 | 27 | 11797 | 30 | |
Unknown | 652 | 2 | 41 | 2 | 693 | 2 | |
Age at menopause (years) | 0.063 | ||||||
< 40 | 2919 | 8 | 188 | 7 | 3107 | 8 | |
40-49 | 9810 | 27 | 776 | 29 | 10586 | 27 | |
50-54 | 11903 | 32 | 831 | 31 | 12734 | 32 | |
55-59 | 4818 | 13 | 346 | 13 | 5164 | 13 | |
60-70 | 623 | 2 | 45 | 2 | 668 | 2 | |
Unknown | 6894 | 19 | 533 | 20 | 7427 | 19 | |
Hormone therapy (HT) usee | <0.001 | ||||||
Never | 13010 | 35 | 825 | 30 | 13835 | 35 | |
Ever | 23920 | 65 | 1891 | 70 | 25811 | 65 | |
Unknown | 37 | 0 | 3 | 0 | 40 | 0 |
Unless otherwise noted, covariate assessment was based on the CTS Q5 survey
Assessment based on the CTS baseline survey
Assessment based on reporting family history (in a first degree relative) on any of the CTS surveys from baseline through the Q4 survey
Assessment based on ever reporting use of HT on any of the CTS surveys from baseline through the Q5 survey
Average strenuous and moderate physical activity during past three years as reported on Q5 survey