Table 1.

Receiver operating characteristic (ROC) curves used to predict HA with IR determined by various parameters

IR‐relevant parameters	N	HT‐LCMS			HT‐CLIA
		AUC	95% CI	P value	AUC	95% CI	P value
IFG	332	0.582	0.521‐0.643	0.010	0.535	0.469‐0.601	0.296
IGT	210	0.565	0.487‐0.644	0.113	0.491	0.41‐0.572	0.824
HIN	332	0.714	0.658‐0.770	0.000	0.447	0.383‐0.511	0.110
Increased HOMA‐IR	332	0.647	0.587‐0.707	0.000	0.458	0.392‐0.523	0.202
INS peak shift	204	0.532	0.451‐0.614	0.442	0.540	0.457‐0.622	0.347
AN	178	0.558	0.474‐0.643	0.185	0.496	0.409‐0.583	0.925

Bold values be of statistically significance.

AN, acanthosis nigricans; AUC, area under the curve; CI, confidence interval; HA, hyperandrogenism; HIN, hyperinsulinemia; HOMA‐IR, fasting glucose (mmol/L) × fasting insulin (mIU/L)/22.5, homeostatic model assessment of IR; HT‐CLIA, HA group with TT ≥2.39 nmol/L determined by CLIA; HT‐LCMS, HA group with TT ≥1.85 nmol/L determined by LC‐MS/MS; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; IR, insulin resistance.