Figure 3.

LncRNA ANRIL negatively correlated with inflammatory cytokines in AECOPD patients. LncRNA ANRIL expression was negatively associated with TNF‐α (A), IL‐1β (B), IL‐8 (D), IL‐17A (E), and LTB‐4 (F), while it numerically negatively correlated with IL‐6 (C), but without statistical significance. The correlation was determined by Spearman test. P < 0.05 was considered significant. LncRNA ANRIL, long noncoding RNAs antisense noncoding RNA in the INK4 locus; AECOPD, acute exacerbations of chronic obstructive pulmonary disease; TNF‐α, tumor necrosis factor‐α; IL‐1β, interleukin (IL)‐1β; LTB4, leukotriene B4