Figure 5.

LncRNA ANRIL negatively correlated with GOLD stage in AECOPD patients but not in stable COPD patients. LncRNA ANRIL expression was negatively associated with GOLD stage in AECOPD patients (A), whereas no correlation was found in stable COPD patients (B). The comparison was determined by Kruskal‐Wallis H rank sum test. P < 0.05 was considered significant. LncRNA ANRIL, long noncoding RNAs antisense noncoding RNA in the INK4 locus; GOLD, global initiative for chronic obstructive lung disease; AECOPD: acute exacerbations of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease