Table 1.
The allele and genotype frequencies of SNPs lncRNA‐H19 in case and control subjects in three heredity models
| Gene polymorphism |
Case n = 150 (%) |
Control n = 100 (%) |
Total n = 250 |
OR | CI 95% | P‐value | |
|---|---|---|---|---|---|---|---|
| Down | Up | ||||||
| lncRNA‐H19 (rs217727 C>T) | |||||||
| Co‐dominant | |||||||
| CC | 116 (57%) | 86 (43%) | 202 | ||||
| CT | 29 (67%) | 14 (33%) | 43 | 0.651 | 0.325 | 1.306 | 0.225 |
| TT | 5 (100%) | 0 (—) | 5 | 0.959 | 0.924 | 0.995 | 0.056 |
| Recessive | |||||||
| TT | 5 (100%) | 0 (—) | 5 | 0.967 | 0.938 | 0.996 | 0.065 |
| TC + CC | 145 (59%) | 100 (41%) | 245 | ||||
| Dominant | |||||||
| CC | 116 (57%) | 86 (43%) | 202 | 1.800 | 0.910 | 3.561 | 0.088 |
| TC + TT | 34 (71%) | 14 (29%) | 48 | ||||
| Frequency of C allele | 261 (58%) | 186 (42%) | 447 | 1.985 | 1.048 | 3.761 | 0.033 |
| Frequency of T allele | 39 (74%) | 14 (26%) | 53 | ||||
| lncRNA‐H19 (rs3741219 T>C) | |||||||
| Co‐dominant | |||||||
| TT | 119 (60%) | 80 (40%) | 199 | ||||
| TC | 24 (59%) | 17 (42%) | 41 | 1.054 | 0.532 | 2.806 | 0.881 |
| CC | 7 (70%) | 3 (30%) | 10 | 0.638 | 0.160 | 2.539 | 0.520 |
| Recessive | |||||||
| CC | 7 (70%) | 3 (30%) | 10 | 1.583 | 0.399 | 6.727 | 0.510 |
| CT + TT | 143 (60%) | 97 (40%) | 240 | ||||
| Dominant | |||||||
| TT | 119 (60%) | 80 (40%) | 199 | 1.042 | 0.555 | 1.956 | 0.898 |
| CT + CC | 31 (61%) | 20 (39%) | 51 | ||||
| Frequency of T allele | 262 (60%) | 177 (40%) | 439 | 1.116 | 0.643 | 1.938 | 0.696 |
| Frequency of C allele | 38 (62%) | 23 (38%) | 61 | ||||