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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Epilepsy Res. 2019 Jan 7;150:46–57. doi: 10.1016/j.eplepsyres.2019.01.001

Fig. 2. Flowchart of the MRI data acquisition harmonization at the three study sites (UEF, yellow; Melbourne, purple; UCLA, green).

Fig. 2.

MR protocol editing was performed during the first months before the onset of the animal follow-up study. The initial version of the MRI protocol was revised based on the feedback from the consortium and from the MRI experts at each center. Data was shared at each step allowing changes to be made for image artifacts and differences in signal properties by tailoring the sequences. Several optimization rounds among the hands-on MRI experts took place. Finally, pilot data demonstrated comparable image quality between sites, and the experiments on the first animal cohort of the study were started. Monitoring of the consistent data quality during the longitudinal follow-up, repeatability and hardware stability were conducted by interim analysis and additional test measurement pattern with liquid phantom.