Hippocampal atrophy rate in Aβ+ and Aβ− CN and MCI subjects. The percentage of hippocampal atrophy rate attributable to Aβ status was calculated from the difference in hippocampal atrophy rate between Aβ+ and Aβ− subgroups. Aβ was measured using florbetapir PET. *P < .01, **P < .001, and ***P < .0001. Abbreviations: NC, normal cognition; MCI, mild cognitive impairment; PET, positron emission tomography. Reproduced with permission from [128].