The correspondence among three measures of cognitive dysfunction in Alzheimer’s disease. Latent AD–related cognitive dysfunction was calculated using Item Response Theory methodologies estimated from ADAS-cog, MMSE, and CDR-SOB. Abbreviations: AD, Alzheimer’s disease; ADAS-cog, Alzheimer’s Disease Assessment Scale–cognitive subscale; CDR-SOB, Clinical Dementia Rating–Sum of Boxes; MMSE, Mini–Mental State Examination. Reproduced with permission from [21].