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. Author manuscript; available in PMC: 2019 Oct 29.
Published in final edited form as: Alzheimers Dement. 2017 Mar 22;13(4):e1–e85. doi: 10.1016/j.jalz.2016.11.007

Fig. 27.

Fig. 27.

Cumulative survival of individuals based on their high entorhinal cortex volume (ECV) and level of white-matter hyperintensities (WMHs). ADNI MCI subjects were dichotomized according to the median split of their ECV and levels of WMH. Individuals with high ECV and low WMH had low likelihood of rapid decline, whereas subjects with low ECV and low WMH or low ECV and high WMH appear to progress most rapidly. Solid line indicates high ECV, low WMH; dashed line indicates high ECV, high WMH; dotted line indicates low ECV, low WMH; dash-dotted line indicates low ECV, high WMH. Abbreviations: ADNI, Alzheimer’s Disease Neuroimaging Initiative; MCI, mild cognitive impairment. Reproduced with permission from [297].