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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Sep 5;39(11):2353–2366. doi: 10.1161/ATVBAHA.119.312754

Figure 3. Human Peripheral Blood from Recovered Post-Septic Patients Demonstrates Decreased MLL1.

Figure 3.

A: Peripheral blood leukocytes (30 mL) were collected from post-sepsis patients and control subjects without documented history of sepsis. The average time of recovery since sepsis was 1280 days (range 14-2431 days). No statistical differences were found between groups with respect to sex, age, or comorbid conditions. MLL1 gene expression was measured by qPCR (n = 33 patients in post-sepsis cohort and 61 patients in control). Data are presented as the mean±SEM. *p<0.05. For human peripheral blood leukocytes Cox regression analysis with a fixed covariate (sepsis vs non-septic) was used in which gene expression data from each septic donor was paired with expression data from a healthy age and sex matched control.