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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: Nature. 2019 Oct 23;574(7779):543–548. doi: 10.1038/s41586-019-1644-y

Figure 2. Excitatory neurons and microglia are affected in ABX mice.

Figure 2.

a, Single nucleus profiles colored by cell type (see Extended Data Fig. 5 for annotations). n = 2/group. b,c, Differentially expressed genes (blue dots: z-test calculated on coefficients of mixed linear model, Bonferroni-corrected P<10−7) of ABX versus Ctrl in excitatory neuron subset 1 (exPFC1) (b) or microglia (c). d, GO terms significantly enriched among the differentially expressed genes in microglial cluster in (c).