Table 3. Development of severe IVH, mortality, and neonatal seizure.
| Outcomes | Variables | Adjusted ORa (95% CI) | Pa |
|---|---|---|---|
| IVH (grade ≥ 3) | HCA | 1.21 (0.71–2.09) | 0.484 |
| AS | 0.82 (0.53–1.26) | 0.362 | |
| HCA × AS | 0.47 (0.25–0.88) | 0.019 | |
| Mortality | HCA | 0.51 (0.29–0.91) | 0.022 |
| AS | 0.59 (0.39–0.90) | 0.014 | |
| HCA × AS | 1.41 (0.75–2.65) | 0.292 | |
| Seizure | HCA | 0.93 (0.55–1.57) | 0.782 |
| AS | 0.57 (0.37–0.86) | 0.008 | |
| HCA × AS | 1.05 (0.57–1.93) | 0.870 |
IVH, intraventricular hemorrhage; HCA, histological chorioamnionitis; AS, antenatal steroids. OR, odds ratio; CI, confidence interval.
aAdjusted values were obtained from multivariable logistic regression models with an interaction term of HCA and AS including the following variables: HCA, AS, HCA × AS, maternal age, gravidity, parity, maternal hypertension, maternal diabetes, rupture of membranes > 18 h, caesarean delivery, gestational age, birth weight, infant sex, and small for gestational age.