Table 5. Statistically significant differences between current vs. never and former smokers at the end of follow-up.
Variables included in Table 1 not shown here were not significantly different between these two groups at this time point.
| CURRENT SMOKERS | NEVER AND FORMER SMOKERS | P value | |
|---|---|---|---|
| n = 89 (47.3%) | n = 99 (52.7%) | ||
| Demographic characteristics& toxic exposures | |||
| Age in years. mean (SD) | 53.3±5.1 | 57.0±7.7 | <0.001 |
| BMI in kg/m2 | 23.4±3.5 | 25.5±4.2 | <0.001 |
| Pack-years | 36 [27–46] | 25 [15–35] | 0.002 |
| Alcohol abuse | 23 (25.8%) | 14 (14.1%) | 0.044 |
| Marijuana use | 34 (38.2%) | 8 (8.1%) | <0.001 |
| Cocaine use | 0.003 | ||
| Never | 33 (37.1%) | 63 (63.6%) | |
| Former | 51 (57.3%) | 30 (30.3%) | |
| Current | 5 (5.6%) | 6 (6.1%) | |
| Heroine use | <0.001 | ||
| Never | 50 (56.2%) | 79 (79.8%) | |
| Former | 39 (43.8%) | 20 (20.2%) | |
| Current | 0 (0.0%) | 0 (0.0%) | |
| HIV Data | |||
| HIV Risk group. n (%) | 0.003 | ||
| Intravenous drugs | 37 (41.6%) | 20 (20.2%) | |
| Homosexual | 27 (30.3%) | 39 (39.4%) | |
| Heterosexual | 24 (27.0%) | 36 (36.4%) | |
| Others | 1 (1.1%) | 4 (4.0%) | |
| Years with HIV+. mean (SD) | 20.1±5.4 | 18.1±4.7 | 0.007 |
| CD4 nadir. median (IQR) | 301 [187–528] | 194 [65–422] | 0.003 |
| CD4. median (IQR) | 728 [516–912] | 598 [429–823] | 0.018 |
| CD4 <200 (MONTH) | 0 [0–12] | 6 [0–20] | 0.002 |
| CD4 nadir < 200 | 24 (27.0%) | 53 (53.5%) | <0.001 |
| Hepatitis C. n (%) | 42 (47.2%) | 25 (25.3%) | 0.002 |
| Comorbidities | |||
| Diabetes. n (%) | 6 (6.7%) | 16 (16.2%) | 0.045 |
| HTA. n (%) | 23 (25.8%) | 44 (44.4%) | 0.008 |
| Respiratory Symptoms & Lung Function | |||
| SGRQ. median (IQR) Total | 12.6 [5.5–20.9] | 4.7 [0.9–10.8] | <0.001 |
| FEV1-postBD (%). mean (SD) | 87.8±15.4 | 92.4±13.8 | 0.030 |
| FEV1/FVC postBD. mean (SD) | 71.4±9.19 | 76.6±8.2 | <0.001 |
| DLCO (%). mean (SD) | 69.5±12.9 | 80.1±14.9 | <0.001 |
| DLCO <80% | 68 (76.4%) | 45 (45.5%) | <0.001 |
| WT6M (%). mean (SD) | 93.32±10.38 | 104.0±31.3 | 0.004 |
| FEV1 decline (ml), median (IQR) | -61.3 [-97.6;-32.7] | -47.8 [-82.7;-25.6] | 0.088 |
| FEV1decline > 30 ml/year, n (%) | 69 (77.5%) | 69 (69.7%) | 0.225 |