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. 2019 Oct 17;15(10):e1008424. doi: 10.1371/journal.pgen.1008424

Fig 4. SKM-Barr2-KO mice show increased exercise-induced glycogen breakdown and impaired post-exercise glucose tolerance.

Fig 4

Male adult SKM-Barr2-KO and control mice consuming normal chow were run on a treadmill for 1 h following the protocol illustrated in (A). (B) GTT (2 g/kg glucose i.p.) performed after the treadmill exercise. (C-E) Western blotting studies and SKM glycogen content. Mice were subjected to the experimental protocol shown in (A), injected with glucose (2 g/kg glucose i.p.), and then euthanized for the isolation of SKM tissues. (C, D) Western blotting studies. (E) SKM glycogen content. Data are presented as mean ± SEM (5–8 mice per group). *P < 0.05, ***P < 0.001 (Student’s unpaired t-test); #P = 0.03 (2-way-ANOVA). Quad, quadriceps muscle.