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. 2019 Sep 26;39(11):2338–2352. doi: 10.1161/ATVBAHA.119.313246

Figure 4.

Figure 4.

Low-density lipoprotein (LDL) profiles of 3 patients with homozygous familial hypercholesterolemia (FH). Lipoproteins were separated on density using density-gradient ultracentrifuge (DGUC). Subsequently, the pooled LDL fractions were subjected to fast-protein liquid chromatography (FPLC) revealing the presence of regular LDL and larger LDL in patients with homozygous FH. HDL indicates high-density lipoprotein; and VLDL, very-low–density lipoproteins.