Table A1.
Age-Truncated Results of Multivariable Models for Anterior Laminar Cribrosa Surface Depth Including Race and Racial Interactions
|
Parameter |
Defined by Scleral Reference Plane |
Defined by Bruch's Membrane Opening Reference Plane |
||
|
Estimate (SE) |
P
Value |
Estimate (SE) |
P
Value |
|
| Intercept | 405.2 (21.3) μm | <0.001 | 467.7 (21.1) μm | <0.001 |
| BMO area | 74.4 (26.5) μm/mm2 | 0.0050 | 74.3 (26.2) μm/mm2 | 0.0046 |
| Visual field mean defect | −8.1 (2.4) μm/dB | 0.0006 | −8.5 (2.5) μm/dB | 0.0006 |
| Intraocular pressure | 9.7 (5.7) μm/mm Hg | 0.0888 | 10.7 (5.7) μm/mm Hg | 0.0594 |
| Age | −3.8 (1.7) μm/y | 0.0263 | −4.5 (4.7) μm/y | 0.0305 |
| Sex, male reference | −43.4 (25.4) μm | 0.0873 | −50.5 (25.8) μm | 0.0504 |
| Race, AD reference | −78.0 (21.8) μm | 0.0004 | −76.0 (22.0) μm | 0.0005 |
| Race*IOP, AD reference | −11.8 (7.7) μm/mm Hg | 0.1256 | −10.5 (7.9) μm/mm Hg | 0.1826 |
| Race*age | 5.9 (2.4) μm/y | 0.0139 | 6.2 (2.8) μm/y | 0.0235 |
| Race*visual field | 4.7 (3.6) μm/dB | 0.1886 | 5.7 (3.6) μm/dB | 0.1201 |
| Race*BMO area | −40.8 (42.3) μm/mm2 | 0.3351 | −44.8 (42.4) μm/mm2 | 0.1201 |
| Choroidal thickness | Not included | – | 0.71 (0.27) μm/μm | 0.0930 |
| Race*choroidal thickness | Not included | – | −0.08 (0.31) μm/μm | 0.9020 |
Analysis performed eliminating AD individuals below the lowest age of the ED group (49 years). Mean ages of truncated groups were similar across race, P = 0.4566.