Table 1. Estimates of some key biological parameters and comparison with the literature.

The estimates of the biological parameters (middle column) are shown as the median and 95% credible interval (CI) of the marginal posterior parameter distribution (Figure 1—figure supplement 15). Estimates from the literature (third column) are shown in the format of either ‘mean estimate (95% confidence interval)’ or ‘mean estimate [minimum – maximum estimate]’ or simply ‘a low estimate – a high estimate’. Note some quoted estimates are from either in vivo or in vitro studies of P. falciparum. The source data and computer code with instructions of implementation to generate our model estimates (middle column) in Table 1 are fully publicly available at https://doi.org/10.26188/5cde4c26c8201.

Biological parameters (unit)	Median estimate (95% CI)	Estimates in the literature
Sexual commitment rate (%/asexual replication cycle)	0.54 (0.30–1.00)	11 (6.2–15.8) (Filarsky et al., 2018) (in vitro) 0.64 [0.027–13.5] (Eichner et al., 2001) (in vivo)
Gametocyte sequestration time (days)	8.39 (6.54–10.59)	7.4 [4 – 12] (Eichner et al., 2001) (in vivo)
Circulating gametocyte lifespan (days)	63.5 (12.7–1513.9)	16–32 (Gebru et al., 2017) (in vitro) 6.4 [1.3–22.2] (Eichner et al., 2001) (in vivo)
Parasite multiplication factor (per asexual replication cycle)	21.8 (17.6–26.9)	10–33 (Wockner et al., 2017) (in vivo) 16.4 (15.1–17.8)a (in vivo)

^a JS McCarthy, personal communication, May 2019.