Table 5.

Number of patients with an available proxy assessment at any possible combination of timepoints during the study (N=2213).

Timepoints during study				Patients n (%)
E1a	E2b	E3c	E4d
Yes	Yes	Yes	Yes	155 (7.00)
Yes	Yes	Yes	No	159 (7.18)
Yes	Yes	No	Yes	36 (1.63)
Yes	Yes	No	No	223 (10.08)
Yes	No	Yes	Yes	22 (0.99)
Yes	No	Yes	No	36 (1.63)
Yes	No	No	Yes	9 (0.41)
Yes	No	No	No	320 (14.46)
No	Yes	Yes	Yes	19 (0.86)
No	Yes	Yes	No	33 (1.49)
No	Yes	No	Yes	5 (0.23)
No	Yes	No	No	74 (3.34)
No	No	Yes	Yes	9 (0.41)
No	No	Yes	No	17 (0.77)
No	No	No	Yes	8 (0.36)
No	No	No	No	1088 (49.16)

^aTimepoint 1.

^bTimepoint 2.

^cTimepoint 3.

^dTimepoint 4.