Table 6.
Comparison of quality of life (QoL) nonparticipants and QoL participants at timepoint 1 (E1) in the overall cohort (N=2213).
| Characteristics | QoL overall sample at registration | ||
| QoL nonparticipants (n=844) | QoL participants (n=1369) | ||
| Sex (male), n (%) | 498 (59.00) | 803 (58.66) | |
| Age (years) | |||
| ≥5-<16, n (%) | 523 (61.97) | 871 (63.62) | |
| ≥16, n (%) | 321 (38.03) | 498 (35.94) | |
| Overall mean (SD) | 15.4 (5.6) | 15.0 (5.10) | |
| Study groups, n (%) | |||
| Children’s Oncology Group | 380 (45.02) | 784 (57.27) | |
| Cooperative Osteosarcoma Study group | 242 (28.67) | 241 (17.60) | |
| European Osteosarcoma Intergroup | 199 (23.58) | 252 (18.41) | |
| Scandinavian Sarcoma Group | 23 (2.73) | 92 (6.72) | |
| Tumor location, n (%) | |||
| Missing | 9 (1.07) | 7 (0.51) | |
| Upper extremity | 130 (15.40) | 188 (13.73) | |
| Lower extremity | 700 (82.94) | 1159 (84.66) | |
| Other | 5 (0.59) | 15 (1.10) | |
| Lung metastases, n (%) | |||
| Missing | 9 (1.07) | 6 (0.44) | |
| Yes | 125 (14.81) | 170 (12.42) | |
| Noa | 710 (84.12) | 1193 (87.14) | |
| Other (nonlung) metastases, n (%) | |||
| Missing | 11 (1.30) | 6 (0.44) | |
| Yes | 35 (4.15) | 37 (2.70) | |
| Noa | 798 (94.55) | 1326 (96.86) | |
| Pathological fracture at diagnosis, n (%) | |||
| Missing | 11 (1.30) | 7 (0.51) | |
| No | 725 (85.90) | 1202 (87.80) | |
| Yes | 108 (12.80) | 160 (11.69) | |
aPossible metastases were combined with no metastases.