Figure 4.

The sympathetic inhibitory effect of ghrelin after myocardial infarction (MI). Transient responses in cardiac sympathetic nervous activity (SNA) in sham rats (closed circles) and three groups of MI rats: untreated (closed squares), ghrelin-treated immediately after MI (open circles), and ghrelin-treated 2 hours after MI (open squares). Immediately after MI or 2 hours after MI, ghrelin treatment effectively reduced the up-regulated SNA. *Significantly different from before MI (time 0) (P < 0.05). Adapted from Schwenke et al.²⁰⁾