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Matrix implantation in a mice calvarial defect model: At week 4 and 8, animals were scarified and calvarial samples were harvested: top panel four weeks (A) digital photograph and (B) X-ray image. Bottom panel eight weeks (C) digital photograph and (D) X-ray image. (R and L) indicates right side (PLGA matrix) and left side (hybrid matrix) of defect, respectively.
