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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Neuroimage. 2019 Sep 4;202:116162. doi: 10.1016/j.neuroimage.2019.116162

Table 2. CBF, CT/Vo, APOE, and Memory.

Note: Only variables of interest are included in table; All continuous independent variables were standardized; APOE= Apolipoprotein E gene; CBF= Cerebral blood flow; CT= Cortical thickness; Vo= Volume; EC= Entorhinal Cortex; Hc= Hippocampus; β= Standardized regression coefficient; CI= confidence interval; bs= Bootstrapped with 5000 replications; t= t-statistic. The 95% confidence interval of the coefficient was derived using the bootstrap bias-adjusted and accelerated bootstrap interval; +Denotes significant at p<0.10; *Denotes significance at p<0.05; **Denotes significance at p<0.01

Independent Variable β 95% CI (bs) s.e. (bs) t p-value
APOE −0.375 (−0.749, −0.019) 0.167 2.176 0.032*
Left EC CT 0.092 (−0.093, 0.280) 0.184 0.935 0.352
Left EC CBF 0.029 (−0.183, 0.197) 0.092 0.282 0.778
APOE*Left EC CT −0.228 (−0.566, 0.084) 0.165 1.345 0.182
APOE*Left EC CBF −0.115 (−0.482, 0.176) 0.156 0.705 0.482
Left EC CT*Left EC CBF −0.241 (−0.423, −0.050) 0.092 2.302 0.023*
APOE*Left EC CT*Left EC CBF 0.488 (0.220, 0.761) 0.148 3.338 0.001**
APOE −0.416 (−0.793, −0.064) 0.182 2.426 0.017*
Right EC CT −0.039 (−0.219, 0.149) 0.092 0.409 0.683
Right EC CBF 0.038 (−0.166, 0.277) 0.114 0.357 0.722
APOE*Right EC CT 0.085 (−0.303, 0.467) 0.195 0.454 0.650
APOE*Right EC CBF −0.266 (−0.590, 0.064) 0.168 1.557 0.123
Right EC CT*Right EC CBF −0.117 (−0.346, 0.145) 0.124 0.970 0.334
APOE*Right EC CT*Right EC (−0.270, 0.526)
CBF 0.169 0.206 1.050 0.296
APOE −0.303 (−0.645, 0.062) 0.178 1.821 0.071 +
Left Hc Vo −0.007 (−0.196, 0.171) 0.094 0.071 0.943
Left Hc CBF 0.024 (−0.172, 0.200) 0.094 0.260 0.795
APOE*Left Hc Vo 0.011 (−0.330, 0.371) 0.178 0.070 0.943
APOE*Left Hc CBF −0.231 (−0.711, 0.158) 0.218 1.280 0.203
Left Hc Vo*Left Hc CBF 0.037 (−0.151, 0.214) 0.092 0.384 0.702
APOE*Left Hc Vo*Left Hc CBF 0.076 (−0.354, 0.552) 0.228 0.405 0.686
APOE −0.290 (−0.786, 0.002) 0.182 1.717 0.089+
Right Hc Vo −0.088 (−0.097, 0.268) 0.102 0.904 0.368
Right Hc CBF 0.079 (−0.101, 0.263) 0.092 0.864 0.390
APOE*Right Hc Vo 0.049 (−0.307, 0.415) 0.180 0.270 0.787
APOE*Right Hc CBF −0.343 (−0.797, 0.032) 0.205 1.844 0.068+
Right HC Vo*Right Hc CBF −0.152 (−0.369, 0.018) 0.096 1.784 0.077+
APOE*Right Hc Vo*Right Hc CBF 0.220 (−0.154, 0.669) 0.214 1.432 0.155