Table 4.

Clinical features of ALS patients with short and long survival

Characteristic	Short survival (n = 22)	Long survival (n = 23)	OR (95% CI)
Age at onset (years), mean (range)	61.50 (42–82)	54.87 (38–78)	NA
Age group			0.91 (0.30–2.79)
< 60 years, n (%)	11 (50)	12 (52.17)
> 60 years, n (%)	11 (50)	11 (47.82)
Gender			2.25 (0.63–7.45)
Males, n (%)	12 (54.54)	8 (34.78)
Females, n (%)	10 (45.45)	15 (65.21)
Weight at diagnosis (Kg), mean (SD)	52.14 (11.61)	49.22 (12.52)	NA
Weight loss (Kg), mean (SD)	10.77 (5.30)	12.86 (6.83)	1.07 (0.35–3.32)
<10 kg, n (%)	9 (40.90)	9 (39.13)
>10 kg, n (%)	13 (59.09)	14 (60.86)
Comorbidities			0.48 (0.13–1.80)
Yes, n (%)	8 (36.36)	5 (21.73)
No, n (%)	14 (63.63)	18 (78.26)
ODI (mo), mean (SD)	14.27 (8.44)	*** 29.83 (18.80)	14.48 (3.38–53.99)
<24 mo, n (%)	19 (86.36)	7 (30.43)
>24 mo, n (%)	3 (13.63)	16 (69.56)
PEG, n (%)	17 (77.27)	14 (60.86)	2.18 (0.62–7.65)
OGI (mo), mean (SD)	10.94 (8.43)	**27.93 (22.20)	11.92 (2.27–50.84)
<18 mo, n (%)	13 (76.47)	3 (21.42)
>18 mo, n (%)	4 (23.52)	11 (78.57)
MV, n (%)	21 (95.45)	11 (47.82)	22.91 (2.88–254.80)
OMVI (mo), mean (SD)	17.33 (7.73)	*45.00 (20.93)	2.33 (0.58–8.66)
<24 mo, n (%)	12 (57.14)	4 (36.36)
>24 mo, n (%)	9 (42.85)	7 (63.63)
Total cholesterol at onset (mmol/L)	4.13 (0.72)	**5.31 (1.20)	7.33 (1.29–33.10)
< 4.63 mmol/L, n (%)	11 (73.33)	3 (27.27)
>4.63 mmol/L, n (%)	4 (26.66)	8 (72.72)

* p < 0.05 ** p < 0.01, ***p < 0.001. Differences between means of continuous variables were estimated by Student-T test or Mann-Whitney U test. OR values were calculated by bivariate logistic regression analysis. Kg kilograms, mo months, mmol/L millimoles per liter, NA not applicable, OR Odds ratio, PEG percutaneous endoscopic gastrostomy, SD standard deviation, 95% CI, 95% confidence interval