Table 1.
Clinical characteristics of CRC in different sites in the SEER database
| Cecum | Ascending colon | Transverse colon | Descending colon | Sigmoid colon | Rectum | Total | |
|---|---|---|---|---|---|---|---|
| Median age (min–max) | 71 (15–105) | 71 (15–108) | 70 (13–102) | 65 (16-101) | 64 (11–106) | 61 (14–103) | 67 (11–108) |
| Gender (%) | |||||||
| Male | 9.93 | 8.81 | 4.25 | 3.01 | 13.81 | 10.76 | 50.57 |
| Female | 12.62 | 10.48 | 4.54 | 2.62 | 11.95 | 7.22 | 49.43 |
| Race (%) | |||||||
| White | 18.29 | 15.38 | 6.97 | 4.11 | 20.04 | 14.67 | 79.46 |
| Black | 2.92 | 2.47 | 1.13 | 0.89 | 2.67 | 1.43 | 11.51 |
| Asian | 1.09 | 1.19 | 0.56 | 0.55 | 2.61 | 1.57 | 7.57 |
| Other | 0.25 | 0.25 | 0.13 | 0.08 | 0.45 | 0.31 | 1.46 |
| Stage at presentation (%) | |||||||
| Stage 0 | 0.28 | 0.25 | 0.08 | 0.06 | 0.29 | 0.15 | 1.11 |
| Stage I | 4.69 | 4.25 | 1.72 | 1.03 | 6.02 | 4.18 | 21.90 |
| Stage II | 6.73 | 6.69 | 3.25 | 1.84 | 7.11 | 4.71 | 30.32 |
| Stage III | 7.23 | 5.77 | 2.53 | 1.87 | 8.39 | 7.27 | 33.06 |
| Stage IV | 3.61 | 2.33 | 1.20 | 0.83 | 3.95 | 1.67 | 13.60 |
| Histologic subtype (%) | |||||||
| Adenocarcinoma | 19.23 | 16.54 | 7.73 | 5.13 | 24.21 | 16.70 | 89.54 |
| Mucinous adenocarcinoma | 2.59 | 2.20 | 0.88 | 0.42 | 1.30 | 0.97 | 8.37 |
| Other | 0.73 | 0.55 | 0.18 | 0.08 | 0.25 | 0.31 | 2.10 |
| Histologic grade (%) | |||||||
| Well differentiated | 1.92 | 1.66 | 0.74 | 0.50 | 2.34 | 1.38 | 8.54 |
| Moderately differentiated | 14.89 | 12.73 | 6.01 | 4.17 | 19.75 | 13.85 | 71.40 |
| Poorly differentiated | 4.88 | 4.20 | 1.77 | 0.85 | 3.25 | 2.47 | 17.43 |
| Undifferentiated | 0.85 | 0.69 | 0.27 | 0.12 | 0.43 | 0.27 | 2.63 |
| Adequate lymph node examination (more than 12 nodes) (%) | |||||||
| Yes | 18.68 | 16.59 | 6.67 | 4.20 | 18.47 | 11.95 | 76.56 |
| No | 3.81 | 2.66 | 2.10 | 1.43 | 7.23 | 5.93 | 23.17 |
| Missing data | 0.06 | 0.04 | 0.02 | 0.01 | 0.06 | 0.09 | 0.27 |
| Type of surgery (%) | |||||||
| Local excision | 0.02 | 0.03 | 0.01 | 0.02 | 0.11 | 0.26 | 0.45 |
| Partial colectomy | 3.59 | 2.79 | 3.54 | 1.91 | 20.36 | 12.41 | 44.60 |
| Hemicolectomy | 18.39 | 16.05 | 4.90 | 3.48 | 4.24 | 0.72 | 47.77 |
| Total colectomy | 0.29 | 0.22 | 0.19 | 0.15 | 0.51 | 3.69 | 5.04 |
| Other colectomy | 0.24 | 0.18 | 0.14 | 0.08 | 0.52 | 0.79 | 1.94 |
| No surgery | 0.02 | 0.02 | 0.01 | 0.01 | 0.03 | 0.12 | 0.19 |
| Chemotherapy (%) | |||||||
| Yes | 7.33 | 5.52 | 2.74 | 2.14 | 9.93 | 12.41 | 40.07 |
| No/unknown | 15.21 | 13.77 | 6.05 | 3.49 | 15.83 | 5.57 | 59.93 |
| Radiation therapy (%) | |||||||
| Yes | 0.32 | 0.15 | 0.06 | 0.07 | 0.81 | 11.38 | 12.79 |
| No/unknown | 22.23 | 19.14 | 8.73 | 5.56 | 24.95 | 6.60 | 87.21 |
SEER*Stat software (seer.cancer.gov/seerstat) was used to access the SEER data after signing research data agreement. All patients diagnosed with colon and rectal adenocarcinoma from 2006 to 2015 were included. A total of 179,323 CRC patients were included after screening