Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 29;38:434. doi: 10.1186/s13046-019-1427-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — DTX-pretreatment in balb/c nude mice increases CNS metastatic load after intracardiac TCs injection. a Experimental setting of the animal model. b Representative HE and immunohistochemical (wide-spectrum cytokeratin) stainings of established tumor foci (original magnification 10x or 20x). c, d Representative IF-stainings of microenvironmental changes surrounding established tumor foci of different sizes and treatment groups: staining for (c) astrocytes (GFAP), d microglia (Iba1) (images taken with the Eclipse 80i fluorescent microscope; scale bar, 50 μm). e, f One way ANOVA with Kruskal-Wallis test for CNS tumor foci count performed either in (e) HE- or (f) wide-spectrum cytokeratin IHC-staining. Statistical analysis was done using GraphPad Prism software